Facing funding challenges? This blog from Harvard Bioscience explores diverse alternative funding sources for researchers—from private foundations and industry partnerships to international grants and crowdfunding. It also highlights key awards supporting early-career scientists. Discover practical paths to keep your research moving forward, even in uncertain times.
Discover how DSI’s SoHo™ Telemetry System and Panlab behavioral platforms empower Alzheimer’s researchers with synchronized physiological and behavioral data collection. This integrated approach enhances study design, data quality, and insight into disease progression—supporting breakthroughs in preclinical models. In honor of Alzheimer’s Awareness Month, explore how these advanced tools bring you closer to translational success.
Song et al. (2025) conducted a comprehensive genetic analysis of the live-attenuated SA14-14-2 vaccine and its virulent parent strain SA14, identifying key viral factors responsible for their differences in pathogenicity, which could inform future antiviral strategies and broader neurotropic virus research.
The photoelectrochemical research team from the School of Chemistry and Chemical Engineering, led by Professor Chen Shu, Associate Professor Zhang Jie, and Associate Professor Liu Canjun, plan to integrate it with their research focused on single-particle electrochemistry, photo/electrocatalysis, electrochemical sensing, in vivo electroanalytical chemistry, and other biomedical application fields, making it an electrophysiology-electrochemistry multi-function combined platform.
Organoid research is revolutionizing our understanding of human biology by providing three-dimensional, physiologically relevant models of human tissues. Key techniques include patch clamp electrophysiology, microelectrode arrays (MEAs), and optical manipulation, each of which unique advantages for studying the functional properties of organoids.
A recent Eli Lilly study highlights Jacketed External Telemetry (JET) as the superior method for nonclinical QTc assessment, outperforming multilead snapshot recordings in both statistical and pharmacological sensitivity. JET’s ability to capture high-fidelity ECG data from conscious, freely moving animals makes it more clinically relevant and regulatory-aligned. Backed by 2022 ICH E14/S7B updates, JET sets a new standard for cardiac safety in toxicology studies.
Researchers at McGill University in Montreal, Quebec investigated the role of Doublecortin (DCX) in regulating neuronal branching through its influence on tubulin polyglutamylation.
In a move that could reshape the landscape of preclinical drug development, the Food and Drug Administration (FDA) recently announced a plan to phase out its requirement for use of animal models in evaluating monoclonal antibodies (mAbs) and other drug candidates.
The SoHo Telemetry System revolutionizes small animal model research by enabling real-time physiological monitoring alongside behavioral analysis without disrupting natural movement. With wireless efficiency, extended transmission distance, and seamless integration, SoHo enhances studies in stress, neuroscience, sleep, motor disorders, cognition, and metabolism. Researchers gain greater accuracy, efficiency, and reproducibility, making SoHo a game-changer in preclinical research.
Retinitis pigmentosa (RP) and retinal dystrophy are debilitating genetic disorders that lead to progressive vision loss due to the degeneration of photoreceptor cells in the retina. Despite advances in genetic research, effective treatments remain limited, making the development of innovative research models crucial. Organoids and Mesh MEA (microelectrode array, also referred to as multielectrode array) technology from Multi Channel Systems have emerged as powerful tools in studying these diseases, providing insights into retinal function and potential therapeutic approaches.
